| Venue: Empire Stadium, London. |   
| Final | time | +time | L | t.a. | Y |  | 1. Arthur Wint |  JAM | 46.2s |   | 3 | 46.3 | 28 |  | 2. Herb McKenley |  JAM | 46.4s | +0.23 | 2 |   | 26 |  | 3. Mal Whitfield |  USA | 46.9s | +0.66 | 4 |   | 23 |  | 4. Dave Bolen |  USA | 47.2s | +0.90 | 1 |   | 24 |  | 5. Morris Curotta |  AUS | 47.9s | +1.77 | 5 |   | 19 |  | 6. George Guida |  USA | 50.2s | +4.50 | 6 |   | 23 |   
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|   |  | First 3 from each 2 semi-finals progressed to Final. |   
| Semi 1 | time | +time | t.a. | Y |  | 1. Arthur Wint |  JAM | 46.3s |   | 46.5 | 28 |  | 2. Morris Curotta |  AUS | 47.2s | +0.78 |   | 19 |  | 3. Mal Whitfield |  USA | 47.4s | +0.96 |   | 23 |  | 4. George Rhoden |  JAM | 47.7s | +1.26 |   | 21 |  | 5. Jimmy Reardon |  IRL | 47.8s | +1.32 |   | 22 |   
| Semi 2 | time | +time | t.a. | Y |  | 1. Herb McKenley |  JAM | 47.3s |   | 47.3 | 26 |  | 2. Dave Bolen |  USA | 47.9s | +0.67 |   | 24 |  | 3. George Guida |  USA | 48.3s | +1.10 |   | 23 |  | 4. Dennis Shore |  RSA | 48.8s | +1.43 |   | 33 |  | 5. Rosalvo Ramos |  BRA | 49.1s | +1.93 |   | 34 |  | 6. Bob McFarlane |  CAN | 51.7s |   |   | 21 |   
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|   |  | First 3 from each 4 quarter-finals progressed to Semi-Finals. |   
| Quarter 1 | time | +time | Y |  | 1. Mal Whitfield |  USA | 48.0s | 48.2 | 23 |  | 2. George Rhoden |  JAM | 48.6s |   | 21 |  | 3. Rosalvo Ramos |  BRA | 48.7s |   | 34 |  | 4. Les Lewis |  GBR | 49.2s |   | 23 |  | 5. Zvonko Sabolović |  YUG | 49.5s |   | 25 |  | 6. Folke Alnevik |  SWE | 50.6s |   | 28 |   
| Quarter 2 | time | t.a. | Y |  | 1. Arthur Wint |  JAM | 47.7s | 47.9 | 28 |  | 2. Morris Curotta |  AUS | 48.4s |   | 19 |  | 3. Dennis Shore |  RSA | 48.5s |   | 33 |  | 4. Bill Roberts |  GBR | 48.6s |   | 36 |  | 5. Bjørn Vade |  NOR | 49.7s |   | 26 |   
| Quarter 3 | time | t.a. | +time | Y |  | 1. Herb McKenley |  JAM | 48.0s |   | 48.0 | 26 |  | 2. George Guida |  USA | 48.0s | +0.06 |   | 23 |  | 3. Rune Larsson |  SWE | 48.8s |   |   | 24 |  | 4. John Bartram |  AUS | 49.9s |   |   | 23 |  | 5. Francis Schewetta |  FRA | 49.9s |   |   | 28 |  | 6. Marko Račič |  YUG | 52.1s |   |   | 28 |   
| Quarter 4 | time | t.a. | Y |  | 1. Dave Bolen |  USA | 48.0s | 48.1 | 24 |  | 2. Jimmy Reardon |  IRL | 48.3s |   | 22 |  | 3. Bob McFarlane |  CAN | 48.4s |   | 21 |  | 4. Kurt Lundquist |  SWE | 48.4s |   | 22 |  | 5. Derek Pugh |  GBR | 48.8s |   | 22 |  | 6. Jacques Lunis |  FRA | 48.9s |   | 25 |   
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| Heat 1 | time | t.a. | Y |  | 1. Jimmy Reardon |  IRL | 48.4s | 48.4 | 22 |  | 2. Marko Račič |  YUG | 50.5s |   | 28 |  | 3. Chen Yinglang |  CHN | 50.9s |   |   |  | 4. Georgios Karageorgos |  GRE | 54.5s |   | 33 |   
| Heat 2 | time | t.a. | Y |  | 1. Herb McKenley |  JAM | 48.4s | 48.6 | 26 |  | 2. Rune Larsson |  SWE | 49.2s |   | 24 |  | 3. Ferenc Bánhalmi |  HUN | 49.6s |   | 25 |  | 4. Jaime Aparicio |  COL | 50.8s |   | 18 |  | 5. Guillermo Evans |  ARG | 51.8s |   | 25 |   
| Heat 3 | time | t.a. | Y |  | 1. Zvonko Sabolović |  YUG | 49.9s | 49.9 | 25 |  | 2. Kurt Lundquist |  SWE | 50.0s |   | 22 |  | 3. Antonio Pocoví |  ARG | 50.7s |   | 26 |  | 4. Mario Rosas |  COL | 51.4s |   |   |  | 5. Hasso L. |  IRQ | 56.8s |   |   |   
| Heat 4 | time | t.a. | Y |  | 1. George Rhoden |  JAM | 48.4s | 48.7 | 21 |  | 2. Dennis Shore |  RSA | 49.0s |   | 33 |  | 3. Oskar Hardmeier |  SUI | 49.2s |   | 22 |  | 4. Angel García |  CUB | 50.2s |   | 28 |  | 5. Bill Ramsay |  AUS | 50.3s |   |   |   
| Heat 5 | time | t.a. | Y |  | 1. Jacques Lunis |  FRA | 49.3s | 49.3 | 25 |  | 2. Folke Alnevik |  SWE | 50.2s |   | 28 |  | 3. Carlos Monges |  MEX | 50.9s |   | 22 |   
| Heat 6 | time | t.a. | Y |  | 1. Dave Bolen |  USA | 50.1s | 50.2 | 24 |  | 2. John Bartram |  AUS | 50.8s |   | 23 |  | 3. Hazzard Dill |  BER | 53.0s |   | 29 |   
| Heat 7 | time | t.a. | Y |  | 1. Les Lewis |  GBR | 48.9s | 49.0 | 23 |  | 2. Bjørn Vade |  NOR | 49.6s |   | 26 |  | 3. Ernie McCullough |  CAN | 49.9s |   |   |  | 4. Walter Keller |  SUI | 50.3s |   |   |  | 5. Runar Holmberg |  FIN | 50.6s |   | 25 |   
| Heat 8 | time | t.a. | Y |  | 1. Mal Whitfield |  USA | 48.3s |   | 23 |  | 2. Bill Roberts |  GBR | 48.9s |   | 36 |  | 3. Don McFarlane |  CAN | 49.5s |   | 22 |  | 4. Olavi Talja |  FIN | 50.4s |   | 23 |  | 5. Max Trepp |  SUI | 50.9s |   | 24 |   
| Heat 9 | time | t.a. | Y |  | 1. Arthur Wint |  JAM | 47.7s | 47.7 | 28 |  | 2. Francis Schewetta |  FRA | 48.9s |   | 28 |  | 3. John De Saram |  SRI | 51.2s |   | 19 |  | 4. Tauno Suvanto |  FIN | 51.5s |   | 23 |  | 5. Doğan Acarbay |  TUR | 53.0s |   | 21 |   
| Heat 10 | time | t.a. | Y |  | 1. Morris Curotta |  AUS | 49.1s | 49.2 | 19 |  | 2. Rosalvo Ramos |  BRA | 49.2s |   | 34 |  | 3. Raymond Crapet |  FRA | 49.4s |   | 21 |  | 4. Kemal Horulu |  TUR | 51,5s |   |   |   
| Heat 11 | time | t.a. | Y |  | 1. George Guida |  USA | 49.0s | 49.1 | 23 |  | 2. Derek Pugh |  GBR | 49.3s |   | 22 |  | 3. Gustavo Ehlers |  CHI | 49.5s |   | 23 |  | 4. Stefanos Petrakis |  GRE | 54.5s |   | 23 |   
| Heat 12 | time | t.a. | Y |  | 1. Herman Kunnen |  BEL | 50.0s | 50.0 | 23 |  | 2. Bob McFarlane |  CAN | 50.6s |   | 21 |  | 3. Reynir Sigurðsson |  ISL | 51.4s |   | 20 |  | 4. Jaime Itlmann |  CHI | 51.5s |   |   |  | 5. Stylianos Stratakos |  GRE | 52.8s |   | 33 |   
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